Sabya S. Das, Neelam, Kashif Hussain, Sima Singh*, Afzal Hussain, Abdul Faruk and Mike Tebyetekerwa Pages 424 - 443 ( 20 )
Laponite based nanomaterials (LBNMs) are highly diverse regarding their mechanical, chemical, and structural properties, coupled with shape, size, mass, biodegradability and biocompatibility. These ubiquitous properties of LBNMs make them appropriate materials for extensive applications. These have enormous potential for effective and targeted drug delivery comprised of numerous biodegradable materials which results in enhanced bioavailability. Moreover, the clay material has been explored in tissue engineering and bioimaging for the diagnosis and treatment of various diseases. The material has been profoundly explored for minimized toxicity of nanomedicines. The present review compiled relevant and informative data to focus on the interactions of laponite nanoparticles and application in drug delivery, tissue engineering, imaging, cell adhesion and proliferation, and in biosensors. Eventually, concise conclusions are drawn concerning biomedical applications and identification of new promising research directions.
Laponite (LAP), laponite-based nano-materials (LBNMs), applications, composition and characteristics, drug delivery and biosensor.
Department of Pharmaceutical Sciences and Technology, Birla Institute of Technology, Mesra, Ranchi-835215, Jharkhand, Department of Pharmaceutical Sciences, NIMS University, Jaipur-303121, Rajasthan, Gyani Inder Singh Institute of Professional Studies, Dehradun-248003, Uttarakhand, School of Health Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban 4000, Department of Pharmaceutical Sciences and Technology, Birla Institute of Technology, Mesra, Ranchi-835215, Jharkhand, Department of Pharmaceutical Sciences, Hemwati Nandan Bahuguna Garhwal University, Srinagar, Uttarakhand, State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Material Science, Donghua University, Shanghai