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Insights in Nanoparticle-Bacterium Interactions: New Frontiers to Bypass Bacterial Resistance to Antibiotics

[ Vol. 21 , Issue. 28 ]

Author(s):

Roudayna Diab, Bahman Khameneh, Olivier Joubert and Raphael Duval   Pages 4095 - 4105 ( 11 )

Abstract:


Nanotechnology has been revealed as a fundamental approach for antibiotics delivery. In this paper, recent findings demonstrating the superiority of nanocarried-antibiotics over “naked” ones and the ways by which nanoparticles can help to overwhelm bacterial drug resistance are reviewed. The second part of this paper sheds light on nanoparticle-bacterium interaction patterns. Finally, key factors affecting the effectiveness of nanoparticles interactions with bacteria are discussed.

Keywords:

Antibiotic, controlled-release, liposome, nanoparticle, resistance, targeting.

Affiliation:

SRSMC, UMR 7565, CNRSUniversite de Lorraine, Faculte de Pharmacie, 5, rue Albert Lebrun, BP 80403, 54001 Nancy Cedex, France.



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