From NAFLD to NASH and HCC: Pathogenetic Mechanisms and Therapeutic Insights

Author(s):

Samuele De Minicis, Chris Day and Gianluca Svegliati-Baroni   Pages 5239 - 5249 ( 11 )

Abstract:

NAFLD is the most common liver disease worldwide but it is the potential evolution to cirrhosis and hepatocellular carcinoma (HCC) that makes NAFLD of such clinical importance. The current work provides an overview of the main mechanims and potential therapeutical insights involved in NAFLD, NASH, fibrosis and HCC progression.

Keywords:

NAFLD, NASH, fibrosis, microbiota, bacterial translocation.

Affiliation:

, , Department of Gastroenterology, Universita Politecnica delle Marche, Italy.

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