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Endophthalmitis Prophylaxis in Cataract Surgery: Overview of Current Practice Patterns Around the World

[ Vol. 23 , Issue. 4 ]

Author(s):

Andrzej Grzybowski*, Stephen G. Schwartz, Kazuki Matsuura, Stephan O. Tone, Steve Arshinoff, Jonathon Q. Ng, Jay J. Meyer, Wu Liu, Soosan Jacob, Mark Packer, Rifna Lutfiamida, Sjakon Tahija, Paul Roux, Boris Malyugin, Julio A. Urrets-Zavalia, Nicolas Crim, Evangelina Esposito, Pablo Daponte, Fernando Pellegrino, Enrique O. Graue-Hernandez, Aida Jimenez-Corona, Jorge E. Valdez-Garcia, Julio C. Hernandez-Camarena, Nidhi Relhan, Harry W. Flynn, Ravilla D. Ravindran and Anders Behnding   Pages 565 - 573 ( 9 )

Abstract:


Background: Acute-onset postoperative endophthalmitis after cataract surgery remains a rare but important cause of visual loss. There is no global consensus regarding the optimal strategies for prophylaxis of endophthalmitis and practices vary substantially around the world, especially with respect to the use of intracameral antibiotics. The European Society of Cataract & Refractive Surgeons in a randomized clinical trial (2007) reported an approximately 5-fold reduction in endophthalmitis rates associated with the use of intracameral cefuroxime. Despite this report, the use of intracameral antibiotics has not been universally adopted.

Methods: Various endophthalmitis prophylaxis patterns around the world (including the United States, Canada, Australia/New Zealand, Japan, China, India, Indonesia, South Africa, Argentina, Russia, Sweden and Mexico) are compared. Each contributing author was asked to provide similar information, including endophthalmitis rates based on published studies, current practice patterns, and in some cases original survey data. Various methods were used to obtain this information, including literature reviews, expert commentary, and some new survey data not previously published.

Results: Many different practice patterns were reported from around the world, specifically with respect to the use of intracameral antibiotics.

Conclusion: There is no worldwide consensus regarding endophthalmitis prophylaxis with cataract surgery.

Keywords:

Endophthalmitis, endophthalmitis prophylaxis, intracameral antibiotics, topical antibiotics, cataract surgery, cataract surgery complications.

Affiliation:

Department of Ophthalmology, Poznan City Hospital, Poznan, Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, Department of Ophthalmology, Nojima Hospital, Tottori, Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Eye and Vision Epidemiology Research Group, The University of Western Australia Perth, Western, Department of Ophthalmology, University of Auckland, Department of Ophthalmology, Beijing Tongren Hospital Eye Center, Capital Medical University Beijing, Dr. Agarwal`s Eye Hospital, Chennai, Department of Ophthalmology, Oregon Health & Science University, Portland, Oregon, Klinik Meta Nusantara, Jakarta, Klinik Meta Nusantara, Jakarta, Visionmed Eye and Laser Clinic, Johannesburg, S. Fyodorov Eye Microsurgery State Institution, Moscow, Department of Ophthalmology, University Clinic Reina Fabiola, Catholic University of Cordoba, Department of Ophthalmology, University Clinic Reina Fabiola, Catholic University of Cordoba, Department of Ophthalmology, University Clinic Reina Fabiola, Catholic University of Cordoba, Argentine Council of Ophthalmology, Buenos Aires, Department of Ophthalmology, Santa Lucia Hospital, University of Buenos Aires, Instituto de Oftalmologia Fundacion Conde de Valenciana, Mexico City, Instituto de Oftalmologia Fundacion Conde de Valenciana, Mexico City, School of Medicine, Tecnologico de Monterrey, Nuevo Leon, School of Medicine, Tecnologico de Monterrey, Nuevo Leon, Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, Aravind Eye Hospital, Madurai, Umea University, Umea



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