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Systematic Review Article

Treatment of Severe Aplastic Anemia with Porcine Anti-Human Lymphocyte Globulin

[ Vol. 26 , Issue. 22 ]

Author(s):

Qi Lv, Zhang Huiqin, Xiao Na, Liu Chunyan, Shao Zonghong and Wang Huaquan*   Pages 2661 - 2667 ( 7 )

Abstract:


Aplastic anemia (AA) is a bone marrow failure syndrome characterized by pancytopenia. Decreased numbers of hematopoietic stem cells and impaired bone marrow microenvironment caused by abnormal immune function describe the major pathogenesis of AA. Hematopoietic stem cell transplantation and immunesuppressive therapy are the first-line treatments for AA. Porcine anti-lymphocyte globulin (p-ALG) is a new product developed in China. Several studies have shown that p-ALG exhibited good therapeutic effects in AA.

Keywords:

Anemia, aplastic, porcine anti-human lymphocyte globulin, immunosuppressive, treatment, hematopoietic.

Affiliation:

Department of Hematology, General Hospital, Tianjin Medical University, Tianjin 300052, Department of Hematology, General Hospital, Tianjin Medical University, Tianjin 300052, Department of Hematology, General Hospital, Tianjin Medical University, Tianjin 300052, Department of Hematology, General Hospital, Tianjin Medical University, Tianjin 300052, Department of Hematology, General Hospital, Tianjin Medical University, Tianjin 300052, Department of Hematology, General Hospital, Tianjin Medical University, Tianjin 300052



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