Ting Liu and Hua Tang* Pages 3049 - 3058 ( 10 )
The number of human deaths caused by malaria is increasing day-by-day. In fact, the mitochondrial proteins of the malaria parasite play vital roles in the organism. For developing effective drugs and vaccines against infection, it is necessary to accurately identify mitochondrial proteins of the malaria parasite. Although precise details for the mitochondrial proteins can be provided by biochemical experiments, they are expensive and time-consuming. In this review, we summarized the machine learning-based methods for mitochondrial proteins identification in the malaria parasite and compared the construction strategies of these computational methods. Finally, we also discussed the future development of mitochondrial proteins recognition with algorithms.
Mitochondria proteins, malaria parasite, machine learning, database, feature, infection.
Department of Pathophysiology, Key Laboratory of Medical Electrophysiology, Ministry of Education, Southwest Medical University, Luzhou 646000, Department of Pathophysiology, Key Laboratory of Medical Electrophysiology, Ministry of Education, Southwest Medical University, Luzhou 646000