Mariza Vorster, John Buscombe*, Ziauddin Saad and Mike Sathekge Pages 787 - 794 ( 8 )
Both 67Ga and 68Ga-citrates are used to detect a wide spectrum of pathology consisting of various inflammatory, infectious and malignant conditions. Considering the now widespread availability and constantly increasing demand for PET/CT studies,68Ga-citrate is gaining ground in clinical settings and the added value of combined metabolic and anatomical imaging achieved by combining PET with Computed Tomography (CT) to PET/CT makes 68Ga-citrate particularly promising. Despite the tracer's non-specificity, it has demonstrated potential especially in the evaluation of various infectious and inflammatory skeletal- and lung conditions.
In this review, we will focus on the indications and lessons learned from 67Ga, and present the current status for the use of 68Ga-citrate PET/CT in selected inflammation and infectious diseases based on the limited literature available.
Gallium, infection, inflammation, malignant conditions, 68Ga-citrate, Computed Tomography (CT).
Department of Nuclear Medicine, University of Pretoria, Steve Biko Academic Hospital, Pretoria, Department of Nuclear Medicine, University of Pretoria, Steve Biko Academic Hospital, Pretoria, Cambridge University Hospitals, Cambridge University, Department of Nuclear Medicine, University of Pretoria, Steve Biko Academic Hospital, Pretoria