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Synthesis of Tetracyclic Diterpenoids with Pharmacologic Relevance

[ Vol. 22 , Issue. 12 ]

Author(s):

Miroslav Sisa and Tomas Vanek   Pages 1767 - 1807 ( 41 )

Abstract:


This review covers the chemical reactions, synthesis, and biological activities of tetracyclic diterpenoids including ent-kauranes, ent-beyeranes, ent-atisanes, ingenanes, tyglianes, stemodanes, stemaranes, sordarin, salvileucalin B, harringtonolide and hainanolidol. It comprises of the un-reviewed references from the year 2000.

Keywords:

Diterpenoids, synthesis, biological activity, cytotoxicity, anticancer, antifungal, antibacterial, antiviral.

Affiliation:

Laboratory of Plant Biotechnologies, Institute of Experimental Botany, Academy of Sciences of the Czech Republic v.v.i., Rozvojová 263, 165 02 Prague 6 - Lysolaje, Czech Republic.



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