Biomimetic Approaches Towards The Synthesis of Complex Dimeric Natural Products

Author(s):

Paul A. Stanley, Christian Spiteri, Jonathan C. Moore, Andrew S. Barrow, Pallavi Sharma and John E. Moses   Pages 1628 - 1657 ( 30 )

Abstract:

We present a selection of elegant and diverse biomimetic syntheses of complex natural product dimers. The dimerisation pathways discussed encompass the most prevalent strategies, including: Diels-Alder, Aldol, Mannich, conjugate addition, oxidative, radical and photochemical approaches; each underpinned through rational biosynthetic speculation.

Keywords:

Biomimetic, dimer, natural product, total synthesis.

Affiliation:

, , , , , School of Chemistry, University of Nottingham, University Park, Nottingham NG7 2RD, UK

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