Roudayna Diab, Bahman Khameneh, Olivier Joubert and Raphael Duval Pages 4095 - 4105 ( 11 )
Nanotechnology has been revealed as a fundamental approach for antibiotics delivery. In this paper, recent findings demonstrating the superiority of nanocarried-antibiotics over “naked” ones and the ways by which nanoparticles can help to overwhelm bacterial drug resistance are reviewed. The second part of this paper sheds light on nanoparticle-bacterium interaction patterns. Finally, key factors affecting the effectiveness of nanoparticles interactions with bacteria are discussed.
Antibiotic, controlled-release, liposome, nanoparticle, resistance, targeting.
SRSMC, UMR 7565, CNRSUniversite de Lorraine, Faculte de Pharmacie, 5, rue Albert Lebrun, BP 80403, 54001 Nancy Cedex, France.