Daniel J. Wallace Pages 17 - 22 ( 6 )
Cytokines are glycoproteins that serve as chemical messengers between cells. They assist in the regulation of cell growth and repair and also have immune modulating properties. Cytokines play a role in diverse clinical processes and phenomena such as fatigue, fever, sleep, pain, stress and aching. A review of the fibromyalgia literature and related studies suggest that IL-1, IL-6 and IL-8 are dysregulated in the syndrome. Therapies directed against these cytokines may be of potential importance in the management of fibromyalgia.
neuromuscular pain,hypothalamic-pituitary-adrenal (HPA) axis,non-inflammatory process,thyrotropin,lymphocyte proliferation responses,Chronic Fatigue Syndrome,rheumatology
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