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Overview of polyethylene glycol-based materials with a special focus on core-shell particles for drug delivery application

Author(s):

Nasrullah Shah*, Manzoor Hussain, Touseef Rehan, Abbas Khan and Zubair Ullah Khan  

Abstract:


Polyethylene glycols (PEG) are water-soluble nonionic polymeric molecules. PEG and PEG-based materials are used for various important applications such as solvents, adhesives, adsorbents, drug delivery agents, tissue engineering scaffolds, etc. The coating of nanoparticles with PEG forms core-shell nanoparticles. The PEG-based core-shell nanoparticles are synthesized for the development of high-quality drug delivery systems. In the present review, we first explained the basics and various applications of PEGs and PEG-based composites materials and then concentrated on the PEG-based core-shell nanoparticles for biomedical applications specifically their use in drug delivery.

Keywords:

PEGs, PEG-based composite materials, Core-shell particles, Applications, Drug delivery applications

Affiliation:

Department of Chemistry, Abdul Wali Khan University Mardan, Mardan, KP 23200, Department of Chemistry, Abdul Wali Khan University Mardan, Mardan, KP 23200, Department of Biochemistry, Shaheed Benazir Bhutto Women University, Peshawar, KP 45000, Department of Chemistry, Abdul Wali Khan University Mardan, Mardan, KP 23200, Department of Chemistry, Abdul Wali Khan University Mardan, Mardan, KP 23200



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