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An Overview of Copper Nanoparticles: Synthesis, Characterisation and Anticancer Activity

Author(s):

Gowhar Naikoo*, Fatema Al-Mashali, Fareeha Arshad, Naema AL-Maashani, Israr U. Hassan, Zamzam AL Baraami, Lukmanul Hakkim Faruck *, Ahsanulhaq Qurashi, Waqar Ahmed, Abdullah M. Asiri, Alaa A. A. Aljabali, Hamid A. Bakshi* and Murtaza M Tambuwala*  

Abstract:


In this review, we summarised the different methods for copper nanoparticle synthesis, including green methods. We highlighted that the synthesis of the copper nanoparticles from green sources is preferable as they serve as stable and reducing entities. Furthermore, we critically reviewed the effectiveness of copper-based nanoparticles in oncogenic treatments emphasizing breast, lung, colorectal, and skin cancers. Finally, we have summarised the recent progress made in copper-based nanoparticles and their applications to amplify and rectify present cancer treatment options. The synthesis, characterization, stabilization, and functionalization techniques of various copper-based nanoparticles have also been highlighted in each section. In conclusion, the review provides the outlook of copper nanoparticles in cancer diagnostics and therapeutics.

Keywords:

cancer, nanomedicine, copper nanoparticles, diagnostics, therapeutics, cancer treatment, nanomaterials

Affiliation:

Department of Mathematics and Sciences, College of Arts and Applied Sciences, Dhofar University, Salalah 211, Department of Chemical Engineering, College of Engineering, Dhofar University, Salalah 211, Department of Biochemistry, Aligarh Muslim University, U. P. , Department of Chemical Engineering, College of Engineering, Dhofar University, Salalah 211, College of Engineering, Dhofar University, Salalah 211, Department of Chemical Engineering, College of Engineering, Dhofar University, Salalah 211, Department of Urology, Masonic Cancer Center, University of Minnesota, Department of Chemistry, Khalifa University of Science and Technology, Main Campus, Abu Dhabi, PO Box 127788, School of Mathematics and Physics, College of Science, University of Lincoln, Lincoln, LN6 7TS, Department of Chemistry, Faculty of Science, King Abdulaziz University, Jeddah 21589, Department of Pharmaceutics and Pharmaceutical Technology, Yarmouk University-Faculty of Pharmacy, Irbid 566, School of Pharmacy and Pharmaceutical Science, Ulster University, Coleraine, County Londonderry, BT52 1SA, Northern Ireland, School of Pharmacy and Pharmaceutical Science, Ulster University, Coleraine, County Londonderry, BT52 1SA, Northern Ireland



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