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Promises of Lipid-based Drug Delivery Systems in the Management of Breast Cancer

Author(s):

Nagarani Thotakura, Madan Mohan Gupta*, Jitendra Singh Rajawat and Kaisar Raza  

Abstract:


Breast cancer is one of the leading types among the common non-cutaneous malignancies in women. All the curative methods available for its treatment are minimal due to their toxicity issues and dose-related side effects. Various evolving nanotechnology techniques displayed the opportunity to target breast cancer. One such delivery system is lipid-based drug delivery systems (LDDS). This concept is constrained only for the laboratory scale should be shifted to the industrial level targeting the nanomedicine with clinical benefits. This work tried to portray the advancements in the LDDS along with the lipid-based excipients, advantages, disadvantages and applications. It even helped in highlighting the recently developed lipid-based nanocarriers for breast cancer management.

Keywords:

Liposomes, Lipospheres, Lipid polymer hybrid nanoparticles, Nanostructured lipid carriers, Solid lipid nanoparticles, Tumor

Affiliation:

Department of Pharmacy, School of Chemical Sciences and Pharmacy, Central University of Rajasthan, Bandarsindri, Dist. Ajmer, Rajasthan-305817, School of Pharmacy Faculty of Medical Science The University of the West Indies St. Augustine, B N College of Pharmacy, B N University, Udaipur, Rajasthan, Department of Pharmacy School of Chemical Sciences & Pharmacy Central University of Rajasthan Bandarsindri, Distt. Ajmer, Rajasthan-305817



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