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COVID-19 Infection: Epidemiology, Virology, Clinical Features, Diagnosis and Pharmacological Treatment

[ Vol. 27 , Issue. 33 ]

Author(s):

Avneet Kaur, Vijay Bhalla, Mohammed Salahuddin, Syed O. Rahman and Faheem H. Pottoo*   Pages 3551 - 3565 ( 15 )

Abstract:


Coronavirus was first discovered during the year 1930 and since then, various coronaviruses like HKU1, MERS-CoV , NL63 and SARS-CoV-2 have been found to infect humans. The COVID-19 pandemic caused by SARS-CoV-2 is spreading at an alarming rate, thereby creating a health emergency around the world. SARS-CoV2 is reported to be originated from a wet animal market of Wuhan, China. Since then, the world is searching for effective ways to manage and treat the COVID-19 infection. The infections have already multiplied with several folds compared to the number of persons infected by Middle East Respiratory Syndrome Coronavirus and Severe Acute Respiratory Syndrome. In order to fill the gap of knowledge about this virus, several pieces of evidence are required to control it so more lives could be saved. The present review is based on the publicly available literature in order to explore the knowledge regarding epidemiology, virology, diagnosis, clinical features, pharmacological and therapeutic ways to treat the novel coronavirus. This can be helpful in offering novel insights and potential therapeutics for fighting this disease.

Keywords:

Coronavirus, COVID-19, cytokine syndrome, SARS-CoV-2, vaccines, clinical trial.

Affiliation:

Department of Pharmaceutical Chemistry, SGT College of Pharmacy, Shree Guru Gobind Singh Tricentenary University, Gurgaon, Haryana-122505, Department of Pharmaceutical Chemistry, SGT College of Pharmacy, Shree Guru Gobind Singh Tricentenary University, Gurgaon, Haryana-122505, Department of Animal House, Institute for Research and Medical Consultations, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam-31441, Pharmaceutical Medicine, Department of Pharmacology, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi-110062, Department of Pharmacology, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Damman-31441



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