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Molecular Hydrogen Application in Stroke: Bench to Bedside

[ Vol. 27 , Issue. 5 ]

Author(s):

Lei Huang, Cameron Lenahan, Warren Boling, Jiping Tang and John H. Zhang*   Pages 703 - 712 ( 10 )

Abstract:


Stroke is a major cause of mortality and morbidity worldwide. Effective treatments are limited. Molecular hydrogen is emerging as a novel medical gas with therapeutic potential for various neurological diseases, including stroke. We reviewed the experimental and clinical findings of the effects of molecular hydrogen therapy in stroke patients and models. The underlying neuroprotective mechanisms against stroke pathology were also discussed.

Keywords:

Ischemic stroke, intracerebral hemorrhage, subarachnoid hemorrhage, hydrogen gas, hydrogen-rich saline, hydrogen-rich water, antioxidant, neuroprotection.

Affiliation:

Department of Neurosurgery, Loma Linda University, Loma Linda, CA92354, Center for Neuroscience Research, Loma Linda University School of Medicine, Loma Linda, CA, 92324, Department of Neurosurgery, Loma Linda University, Loma Linda, CA92354, Department of Physiology and Pharmacology, Loma Linda University, Loma Linda, CA92354, Department of Neurosurgery, Loma Linda University, Loma Linda, CA92354



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