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Oxidative stress and Parkinson’s disease: New hopes in treatment with herbal antioxidants

[ Vol. 22 , Issue. 2 ]

Author(s):

Amir Sarrafchi, Mahmoud Bahmani, Hedayatollah Shirzad and Mahmoud Rafieian-Kopaei   Pages 238 - 246 ( 9 )

Abstract:


Parkinson's disease (PD) is a neurodegenerative disorder due to dopamine deficit in substatia nigra. PD is mainly a sporadic disease with unestablished etiology. However, exposure to environmental toxins, head trauma, inflammation, and free radicals are potential reasons. Recently, the role of oxidative stress in neurological abnormalities, including PD, has been particularly addressed. Antioxidant remedies, particularly herbal antioxidants, have revealed new perspectives of research and therapy as possible preventive and therapeutic approaches for PD. In this paper, we reviewed the recently published papers on the effects of herbal medicines on PD alongside the pathogenesis of PD with regard to oxidative stress.

Keywords:

Antioxidant, degenerative disorder, herbal medicines, medicinal plants, oxidative stress, Parkinson's disease.

Affiliation:

Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran



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