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Review Article

Antitumor Effects of Curcumin on Cervical Cancer with the Focus on Molecular Mechanisms: An Exegesis

[ Vol. 29 , Issue. 42 ]


Ali Govahi, Neda Zahmatkesh, Omid Pourbagherian, Neda Maleki Khas, Tala Salamzadeh, Hasti Moshtagh Mehr, Esmaeil Babaei* and Mahsa Hajivalili*   Pages 3385 - 3399 ( 15 )


Cervical cancer is one of the most prevalent malignancies among females and is correlated with a significant fatality rate. Chemotherapy is the most common treatment for cervical cancer; however, it has a low success rate due to significant side effects and the incidence of chemo-resistance. Curcumin, a polyphenolic natural compound derived from turmeric, acts as an antioxidant by diffusing across cell membranes into the endoplasmic reticulum, mitochondria, and nucleus, where it performs its effects. As a result, it's been promoted as a chemo-preventive, anti-metastatic, and anti-angiogenic agent. As a consequence, the main goal of the present review was to gather research information that looked at the link between curcumin and its derivatives against cervical cancer.


Curcumin, cervical cancer, herbal remedy, curcumin limitation, curcumin nanoparticles, <i>Curcuma longa</i>.


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