Samuele Laudani, Federica Martina Di Domenico, Nadia Paladino, Ida Guerrera, Giuseppe Grosso* and Justyna Godos Pages 1971 - 1974 ( 4 )
Curcumin is a polyphenol compound widely investigated for its potential health benefits. Clinical evidence from randomized controlled trials shows substantial positive effects in healthy individuals but contrasting results for patients with cardio-metabolic disorders. There is growing evidence that the gut microbiota may play a role in curcumin transformation and absorption of more bioactive compounds, suggesting that the baseline health status (or other unmeasured variables) may explain the observed variability of the results.
Cardiovascular disease, Nox-2, nuclear factor kappa-B, tumor necrosis factor-alpha, bacteroidetes, matrix metalloproteinase 9.