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Review Article

Feeding Pattern, Circadian Rhythm, and Immune Function: What do we know about?

[ Vol. 28 , Issue. 30 ]


Thiago Barros Estanislau, Karsten Kruger, José Cesar Rosa-Neto, Camila S. Padilha, Daniela Caetano Gonçalves, Luciele Guerra Minuzzi and Fábio Santos Lira*   Pages 2478 - 2487 ( 10 )


Feeding pattern is related to health status or chronic diseases, and this depends on the individual’s eating habits. Feeding organized with the right time to start and end during the day, promotes an internal biological rhythm, favoring molecular synchronization of the clock genes, which impose an effect on metabolism and immune cells, creating a physiological response related to a healthy profile. On the other hand, a feeding pattern disorganized, without the right time to start and end eating during the day, might lead to nonsynchronization of the clock genes, a disruption condition, which is related to chronic diseases, such as obesity and diabetes type 2. A strategy that should be adopted to favor molecular synchronization is time-restricted eating (TRE), which can organize the initial and end of the eating patterns during the day. Our review points out some cues that suggest TRE as an efficient strategy for healthy profile and can be a good intervention for the treatment of chronic diseases.


Clock genes, nutrition, immunonutrition, obesity, circadian rhythm, immune function.


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