Li Gao*, Min Cao, Jia-qi Li, Xue-mei Qin and Jiansong Fang* Pages 2925 - 2933 ( 9 )
Cardiovascular disease is a major disease affecting human health, and its pathogenesis is caused by many factors. Through the use of "omics" technology, precision medicine is playing an increasingly important role in the prevention and treatment of cardiovascular diseases. Dialectical treatment with traditional Chinese medicine (TCM will result in personalized treatment, which is consistent with precision medicine to a certain extent. However, due to the multitarget, multipath, and multistep characteristics of TCM, its mechanism of action is not easy to elucidate. Network pharmacology can be used to predict the mechanism, toxicity and metabolic characteristics of TCM. This review summarizes commonly used bioinformatics resources for cardiovascular diseases and TCM, as well as the opportunities and challenges of TCM in cardiovascular precision medicine, with special emphasis on network pharmacology methods.
Cardiovascular disease, omics, traditional Chinese medicine, precision medicine, network pharmacology, transcriptome, metabolomics.
Modern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan 030006, Modern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan 030006, Modern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan 030006, Modern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan 030006, Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou 510405