Pallavi Singh Chauhan, Dhananjay Yadav, Shivam Tayal and Jun-O Jin* Pages 4909 - 4916 ( 8 )
For improvisation of diabetic’s quality of life, nanotechnology is facilitating the development of advanced glucose sensors as well as efficient insulin delivery systems. Our prime focus of the review is to highlight the advancement in diabetic research with special reference to nanotechnology at its interface. Recent studies are more focused on enhancing sensitivity, accuracy, and response by employing metal as well as nanoparticles based glucose sensors. Moreover, the review focuses on nanoscale based approaches i.e. closed-loop insulin delivery systems, which detect any fluctuation in blood glucose levels and allow controlled release of a drug, thus are also called self-regulating insulin release system. Additionally, this review summarizes the role of nanotechnology in the diagnosis and treatment of diabetic complications through little advancement in the existing techniques. To improve health, as well as the quality of life in diabetic’s new sensing systems for blood glucose level evaluation and controlled administration of drugs through efficient drug delivery systems should be explored.
Diabetes mellitus, nanotechnology, blood glucose sensors, nano drug therapy, diabetic complications, sensitivity.
Amity Institute of Biotechnology, Amity University Madhya Pradesh, Gwalior (M.P.), Department of Medical Biotechnology, Yeungnam University, Gyeongsan, 712-749, School of Pharmacy, ITM University, Gwalior, Madhya Pradesh, Research Institute of Cell Culture, Yeungnam University, Gyeongsan 38541